Xinyuan Fan

PhD, Research Associate Professor

Email: xinyuanfan@pku.edu.cn;  Tel: 010-62754127;  Office: C610 

EDUCATION AND EXPERIENCE

2019 – present, Research Associate Professor, Peking University 

2017 – 2019, Associate professor, Nanjing Tech University 

2014 – 2017, Postdoctoral fellow, Peking University 

2013 – University of Pennsylvania, Visiting scholar, Organic chemistry.

2010 – 2014, ICIQ - Institute of Chemical Research of Catalonia (Spain), Ph.D, Organic chemistry  

2003 – 2010, Lanzhou University, BS & MS, Biotechnology and Biochemistry

 

RESEARCH INTERESTS
Chemical biology, Bioorthogonal photocatalysis 
Bioorthogonal chemistry, Photocatalytic chemistry


AWARDS

National Science Fund for Excellent Young Scholars of China 

NG Teng Fong/ Sino Scholarship for Outstanding Youth

Li Ge-Zhao Ning Youth Fund for Life Sciences

 

SELECTED PUBLICATIONS

1. Zhang, X.; Huang, H.; Liu, Y.; Wu, Z.; Wang, F.; Fan, X.*; Chen, P. R.*; Wang, J.*, Optical Control of Protein Functions via Genetically Encoded Photocaged Aspartic Acids. 

J. Am. Chem. Soc. 2023, DOI: 10.1021/jacs.3c03701.

2. Guo, F.; Shan, S.; Gong, X.; Dai, C.; Quan, Z.*; Cheng, X.*; Fan, X.*, Deuteration Degree-Controllable Methylation via a Cascade Assembly Strategy using Methylamine-Water as Methyl Source. 

Chem. Eur. J. 2023, DOI: 10.1002/chem.202301458.

3. Liu, Y.; Ge, Y.; Zeng, R.; Ngai William Shu, C.; Fan, X.*; Chen, P.*, Proximity Chemistry in Living Systems. 

CCS Chem. 2023, 802-813.

4. Liu, Z.; Xie, X.; Huang, Z.; Lin, F.; Liu, S.; Chen, Z.; Qin, S.; Fan, X.*; Chen, P.*, Spatially resolved cell tagging and surfaceome labeling via targeted photocatalytic decaging. 

Chem 2022, 2179-2191.

5. Ngai, W. S. C.; Yang, S.; Zeng, X.; Liu, Y.; Lin, F.; Wang, X.; Zhang, H.; Fan, X.*; Chen, P.*, Bioorthogonally Activatable Base Editing for On-Demand Pyroptosis. 

J. Am. Chem. Soc. 2022, 144 (12), 5411-5417.

6. Luo, H.; Tang, W.; Liu, H.; Zeng, X.; Ngai, W. S. C.; Gao, R.; Li, H.; Li, R.; Zheng, H.; Guo, J.; Qin, F.; Wang, G.; Li, K.; Fan, X.*; Zou, P.*; Chen, P.*, Photocatalytic Chemical Crosslinking for Profiling RNA–Protein Interactions in Living Cells. 

Angew. Chem. Int. Ed. 2022, e202202008. 

7. Huang, Z.; Liu, Z.; Xie, X.; Zeng, R.; Chen, Z.; Kong, L.; Fan, X.*; Chen, P.*, Bioorthogonal Photocatalytic Decaging-Enabled Mitochondrial Proteomics. 

J. Am. Chem. Soc. 2021, 143 (44), 18714-18720. 

8. Wang J; Wang X; Fan X*; Chen P.*, Unleashing the Power of Bond Cleavage Chemistry in Living Systems. 

ACS Cent. Sci. 2021 7 (6), 929-943. 

9. Zhu, J.; Dai, C.; Ma, M.; Yue, Y.; Fan, X.*, Visible light-mediated cross-coupling of electrophiles: synthesis of α-amino amides from isocyanates and ketimines. 

Org. Chem. Front. 2021, 8 (6): 1227-32.

10. Fan, X.*; Gong, X.; Ma, M.; Wang, R.; Walsh, P. J.* “Visible Light-Promoted CO2 Fixation with Imines to Synthesize Diaryl α-Amino Acids”, 

Nat. Commun. 2018, 9(1), 4936.

 

 

For full list of publications, please see: ‪Xinyuan Fan - ‪Google Scholar

https://scholar.google.com/citations?hl=en&user=W2AGqkQAAAAJ&view_op=list_works&sortby=pubdate