Lu Research Group

[79] Jialing Sun†, Junyi Chen†, Yiming Sun, Yingqin Hou, Zhibo Liu*, and Hua Lu*, “On the origin of the low immunogenicity and biosafety of a neutral α-helical polypeptide as an alternative to polyethylene glycol”, Bioactive Mater. 2024, 32, 333-343. (†equal contribution) [PDF]

 

[78] Yi Zhang, Hua Lu,* “Ring-Opening Copolymerization of Hydroxyproline-Derived Thiolactones and Lipoic Acid Derivatives”, Polym. Chem., 2023, 14, 3813-3820. [PDF]

 

[77] Zhengchu Zhang, Wei Xiong*, and Hua Lu*, “Preparation and Material Properties ofα-Helical Polypeptides Crosslinked Hydrogel”, Acta Chim. Sinica 2023, 81, 1113-1119.

    张正初，熊炜*，吕华*，α-螺旋聚氨基酸交联的水凝胶的制备和材料特性，化学学报，2023, 81, 1113-1119. [PDF]

[76] Chunyan Lyu, Wei Xiong, Er-Qiang Cheng*, and Hua Lu*, “Structure-Property Relationship Analysis of D-Penicillamine-Derived β-Polythioesters with Varied Alkyl Side Groups”, Chin. J. Polym. Sci. 2023, 41, 1555-1562. [PDF]

 

[75] Zhuanglin Shen, Yiming Sun, Guoliang Zhu, Gaixia Xu, Zhenqiang Yu, Hua Lu*, and Yantao Chen*, “Molecular Insights into the Improved Bioactivity of Interferon Conjugates Attached to a Helical Polyglutamate”, Langmuir 2023, 39, 6539-6547.  [PDF]

 

[74] Guangqi Wu, Haisen Zhou, Jun Zhang, Zi-You Tian, Xingyi Liu, Shuo Wang, Connor W. Coley, and Hua Lu*, “A high-throughput platform for efficient exploration of functional polypeptide chemical space”, Nat. Synth. 2023, doi: 10.1038/s44160-023-00294-7.  [PDF] 

[73] Shuo Wang, and Hua Lu*, “Ring-Opening Polymerization of Amino Acid N-Carboxyanhydrides with Unprotected/Reactive Side Groups. I. _D-Penicillamine N-Carboxyanhydride”, ACS Macro Lett. 2023, 12, 555-562.  [PDF]

[72] Guo-Qing Jin; Jing-Xiang Wang; Jianhua Lu; Hang Zhang; Yuhang Yao; Yingying Ning; Hua Lu; Song Gao; Jun-Long Zhang* “Two birds one stone: β-fluoropyrrolyl-cysteine S_NAr chemistry enabling functional porphyrin bioconjugation”, Chem. Sci. 2023, 14, 2070-2081.  [PDF]

[71] Wei Xiong, and Hua Lu*, “Recyclable polythioesters and polydisulfides with near-equilibrium thermodynamics and dynamic covalent bonds”, Sci. China. Chem. 2023, 66, 725-738 (Invited Review). [PDF]

[70] Jianhua Lu, Zhun Xu, Hailin Fu, Yao Lin, Huan Wang, Hua Lu^*, “Room-temperature grafting from synthesis of protein–polydisulfide conjugates via aggregation-induced polymerization”, J. Am. Chem. Soc. 2022, 144, 15709-15717. [PDF]

 

[69] Yali Hu, Zi-You Tian, Wei Xiong, Dedao Wang, Ruichi Zhao, Yan Xie, Yu-Qin Song, Jun Zhu, Hua Lu^*, “Water-assisted and protein-initiated fast and controlled ring-opening polymerization of proline N-carboxyanhydride”, Natl. Sci. Rev. 2022, nwac033. [PDF]

[68] Yi Zhang, Hua Lu^*, “Synthesis and applications of hydroxyproline-derived thermoplastic elastomers”, Acta Polym. Sinica 2022, 53, 1123-1130. [PDF]

[67] Haisen Zhou^†, Yaoyi Wang^†, Yingqin Hou, Zhengkui Zhang, Qi Wang, Xiaodong Tian^*, Hua Lu^*, “Co-delivery of cisplatin and chlorin e6 by poly(phosphotyrosine) for synergistic chemotherapy and photodynamic therapy”, Chin. J. Chem. 2022, 40, 2428-2436. (^†equal contribution) [PDF]

 

[66] Chenglong Ge^†, Junliang Zhu^†, Guangqi Wu, Yuan He, Hua Lu^*, Lichen Yin^*, “ROS-responsiveness selenopolypeptide micelles: Peparation, characterization, and controlled drug release”, Biomacromolecules 2022, 23, 2647-2654. (^†equal contribution) [PDF]

 

[65] Meng Yang^†, Zheng-Chu Zhang^†, Fu-Zhen Yuan^†, Rong-Hui Deng, Xin Yan, Feng-Biao Mao, You-Rong Chen^*, Hua Lu^*, Jia-Kuo Yu^*, “An Immunomodulatory Polypeptide Hydrogel for Osteochondral Defect Repair”, Bioactive Materials 2023, 19, 678-689. (^†equal contribution) [PDF]

 

[64] Zhang Chong,  Hua Lu*, “Helical Nonfouling Polypeptides for Biomedical Applications”, Chinese J. Polym. Sci. 2022, 40(5), 433-446. [PDF]

 

 

[63] Chao Dong^†, Guangqi Wu^†, Chen Chen, Xia Li, Rui Yuan, Liang Xu, Hui Guo, Jay Zhang, Hua Lu*, Feng Wang*, “Site-Specific Conjugation of a Selenopolypeptide to Alpha-1-antitrypsin Enhances Oxidation Resistance and Pharmacological Properties”, Angew. Chem. Int. Ed. 2022, 61, e202115241. (^†equal contribution) [PDF]

 

[62] Haisen Zhou, Yaoyi Wang, Hua Lu*, "Intracellular delivery of His-tagged proteins via a hybrid organic–inorganic nanoparticle", Polym. J. 2021, 53, 1259-1267. [PDF]

[61] Zi-You Tian, Zhengchu Zhang, Shuo Wang, Hua Lu*, “A moisture-tolerant route to unprotected α/β-amino acid N-carboxyanhydrides and facile synthesis of hyperbranched polypeptides”, Nat. Commun. 2021, 12, 5810. [PDF]

 

[60] Qingxin Yao^†, Guangqi Wu^†, Hao Hao^†, Hua Lu^*, and Yuan Gao^*, “Redox-mediated reversible supramolecular assemblies driven by switch and interplay of peptide secondary structures”, Biomacromolecules 2021, 22, 2563-2572. (^†equal contribution) [PDF]

[59] Zi-You Tian, Shuo Wang, and Hua Lu^*, “Hydroxyproline-derived biomimetic and biodegradable polymers”, Curr. Opin. Solid State Mater. Sci. 2021, 25, 100902 (Invited Review) [PDF]

[58] Yali Hu, Dedao Wang, Hao Wang, Ruichi Zhao, Yaoyi Wang, Yunfei Shi, Jun Zhu, Yan Xie*, Yu-Qin Song*, Hua Lu*, “An urchin-like helical polypeptide-asparaginase conjugate with mitigated immunogenicity”, Biomaterials 2021, 268, 120606. [PDF]  

[57] Hao Wang, Yali Hu, Yaoyi Wang, Jianhua Lu, Hua Lu*, “Doxorubicin@ PEPylated interferon-polydisulfide: A multi-responsive nanoparticle for enhanced chemo–protein combination therapy”, Giant 2021, 5, 100040. [PDF]  

[56] Wei Xiong, Wenying Chang, Dong Shi, Lijiang Yang, Ziyou Tian, Hao Wang, Zhengchu Zhang, Xuhao Zhou, Er-Qiang Chen,* and Hua Lu*, “Geminal Dimethyl Substitution Enables Controlled Polymerization of Penicillamine-Derived β-Thiolactones and Reversed Depolymerization”, Chem 2020, 6, 1831-1843. [PDF]  (Highlighted by Chem in the same issue)

[55] Yong Shen, Wei Xiong, Yongzheng Li, Zhichao Zhao, Hua Lu* & Zhibo Li*, "Chemoselective Polymerization of Fully Biorenewable α-Methylene-γ-Butyrolactone Using Organophosphazene/Urea Binary Catalysts Toward Sustainable Polyesters", CCS Chem. 2020, 2, 620–630. [PDF]

[54] Helen Yao,‡ Kai Sheng,‡ Jialing Sun, Shupeng Yan, Yingqin Hou, Hua Lu and Bradley D. Olsen *, "Secondary structure drives self-assembly in weakly segregated globular protein-rod block copolymers", Polym. Chem., 2020, 11(17), 3032-3045.(‡equal contribution) [PDF]

 

[53] Jingsong Yuan, Dong Shi, Yi Zhang, Jianhua Lu, Letian Wang, Er-Qiang Chen,* and Hua Lu*, “4-Hydroxy-L-Proline as a General Platform for Stereoregular Aliphatic Polyesters: Controlled Ring-Opening Polymerization, Facile Functionalization, and Site-Specific Bioconjugation”, CCS Chem. 2020, 2, 236-244. [PDF]

[52] Zhilei Ge,† Linjie Guo,† Guangqi Wu,† Jiang Li, Yunlong Sun, Yingqin Hou, Jiye Shi, Shiping Song, Lihua Wang, Chunhai Fan, Hua Lu,* and Qian Li*, “DNA Origami-Enabled Engineering of Ligand-Drug Conjugates for Targeted Drug Delivery”, Small. 2020, e1904857. (†equal contribution)  [PDF]

[51] Dongxiao Yin, Hao Wen, Guangqi Wu, Shaolu Li, Chengyang Liu, Hua Lu*, and Dehai Liang*, “Pegylated Gene Carriers in Serum under Shear Flow”, Soft Matter 2020, 16, 2301-2310. [PDF]

[50] Jianhua Lu, Hao Wang, Ziyou Tian, Yingqin Hou, and Hua Lu*, "Cryopolymerization of 1,2-Dithiolanes for the Facile and Reversible Grafting-from Synthesis of Protein−Polydisulfide Conjugates", J. Am. Chem. Soc. 2020, 142(3), 1217−1221. [PDF]

[49]​ Ruijue Wang†, Kai Sheng†, Yingqin Hou, Jialing Sun and Hua Lu*, "Tailoring Cationic Helical Polypeptides for Efficient Cytosolic Protein Delivery", Chem. Res. Chinese U., 2020, 36(1), 134-138. ( † equal contribution) [PDF]

[48] Wei Xiong, Chong Zhang, Xiaolin Lyu, Hantao Zhou, Wenying Chang, Yu Bo, Erqiang Chen*, Zhihao Shen* and Hua Lu*, "Synthesis of modifiable photo-responsive polypeptides bearing allyloxyazobenzene side-chains", Polym. Chem., 2020, 11, 439-448. [PDF]

[47] Hao Wang, Yingqin Hou, Yali Hu, Jiaxiang Dou, Youqing Shen, Yucai Wang*, and Hua Lu*, "Enzyme-Activatable Interferon−Poly(α-amino acid) Conjugates for Tumor Microenvironment Potentiation", Biomacromolecules 2019, 20, 3000−3008. [PDF]

[46] Guangqi Wu, Chenglong Ge, Xingyi Liu, Shuo Wang, Letian Wang, Lichen Yin* and Hua Lu*, "Synthesis of water soluble and multi-responsive selenopolypeptides via ring-opening polymerization of N-carboxyanhydrides", Chem. Commun., 2019, 55, 7860-7863. [PDF]

[45] Yingqin Hou and Hua Lu*, "Protein PEPylation: A New Paradigm of Protein−Polymer Conjugation“, Bioconjugate Chem. 2019, 30, 1604−1616. [PDF]

[44]​ Jingsong Yuan, Wei Xiong, Xuhao Zhou, Yi Zhang, Dong Shi, Zi-Chen Li, and Hua Lu*, “4-Hydroxyproline-Derived Sustainable Polythioesters: Controlled Ring-Opening Polymerization, Complete Recyclability, and Facile Functionalization”, J. Am. Chem. Soc. 2019, 141, 4928-4935. (ACS Editors’ Choice, Featured as the Front Cover, also highlighted in Spotlights on Recent JACS Publications) [PDF]

[43]​ Chong Zhang†, Jianhua Lu†, Falin Tian†, Lindong Li, Yingqin Hou, Yaoyi Wang, Lingdong Sun*, Xinghua Shi*, and Hua Lu*, “Regulation of the cellular uptake of nanoparticles by the orientation of helical polypeptides”, Nano Res., 2019, 12(4): 889–896 . (†equal contribution) [PDF]

[42]  Yingqin Hou,† Yu Zhou,† Hao Wang,† Jialing Sun,† Ruijue Wang,† Kai Sheng,† Jingsong Yuan,† Yali Hu,‡ Yu Chao,§ Zhuang Liu,§ and Hua Lu*,†, "Therapeutic Protein PEPylation: The Helix of Nonfouling Synthetic Polypeptides Minimizes Antidrug Antibody Generation", ACS Cent. Sci. 2019, 5, 229−236. [PDF]

[41] Shan Su†, Yaoyi Wang†, Fu-Sheng Du*, Hua Lu*, and Zi-Chen Li, “Dynamic Covalent Bond-Assisted Programmed and Traceless Protein Release: High Loading Nanogel for Systemic and Cytosolic Delivery”, Adv. Funct. Mater. 2018, 28, 1805287. (†equal contribution) [PDF]

[40] Jingsong Yuan, Yi Zhang, Zezhou Li, Yaoyi Wang, and Hua Lu*, “A S-Sn Lewis Pair-Mediated Ring-Opening Polymerization of α-Amino Acid N-Carboxyanhydrides: Fast Kinetics, High Molecular Weight, and Facile Bioconjugation”, ACS Macro Lett. 2018, 7, 892-897. [PDF]

[39] Yali Hu, Yingqin Hou, Hao Wang, and Hua Lu*, “Polysarcosine as an Alternative of PEG for Therapeutic Protein Conjugation”, Bioconjugate Chem. 2018, 29, 2232-2238. [PDF]

[38] Chong Zhang†, Jianhua Lu†, Yingqin Hou, Wei Xiong, Kai Sheng, and Hua Lu*, “Investigation on the Linker Length of Synthetic Zwitterionic Polypeptides for Improved Nonfouling Surfaces”, ACS Appl. Mater. Interfaces 2018, 10, 17463-17470. (†equal contribution)  [PDF]

[37] Jingsong Yuan, Yi Zhang, Yue Sun, Zhicheng Cai, Lijiang Yang*, and Hua Lu*, “Salt- and pH-Triggered Helix-Coil Transition of Ionic Polypeptides under Physiology Conditions”, Biomacromolecules 2018, 19, 2089-2097. [PDF]

 

 

[36] Chong Zhang, Jingsong Yuan, Jianhua Lu, Yingqin Hou, Wei Xiong, and Hua Lu*, “From Neutral to Zwitterionic Poly(α-Amino Acid) Nonfouling Surfaces: Effects of Helical Conformation and Anchoring Orientation”, Biomaterials 2018, 178, 728-737. [PDF]

[35] Yingqin Hou, Yu Zhou, Hao Wang, Ruijue Wang, Jingsong Yuan, Yali Hu, Kai Sheng, Juan Feng, Shengtao Yang and Hua Lu*, “Macrocyclization of Interferon–Poly(α-amino acid) Conjugates Significantly Improves the Tumor Retention, Penetration, and Antitumor Efficacy”, J. Am. Chem. Soc., 2018, 140, 1170-1178. [PDF]

[highlighted by ACS Chemical & Engineering News]

[34] Chong Zhang and Hua Lu*, “Efficient Synthesis and Application of Protein-Poly(α-amino acid) Conjugates”, Acta Polymerica Sinica, 2018, 1, 21-31. [PDF]

[33] Shaolu Li†, Yaoyi Wang†, Jingfang Zhang, Wei Wei* and Hua Lu*, “Targeted delivery of a guanidine-pendant Pt(IV)-backboned poly-prodrug by an anisamide-functionalized polypeptide”, J. Mater. Chem. B, 2017, 5, 9546-9557. (†equal contribution) [PDF] 

[32] Wei Xiong, Hantao Zhou, Chong Zhang, Hua Lu*, “An amino acid-based gelator for injectable and multi-responsive hydrogel”, Chinese Chemical Letters, 2017, 28, 2125–2128. [PDF]

[31] Yingqin Hou†, Yaoyi Wang†, Ruijue Wang, Weier Bao, Xiaobo Xi, Yunlong Sun, Shengtao Yang, Wei Wei* and Hua Lu*, “Harnessing Phosphato-Platinum Bonding Induced Supramolecular Assembly for Systemic Cisplatin Delivery”, ACS Appl. Mater. Interfaces, 2017, 9 (21), 17757–17768. (†equal contribution) [PDF]

[30] Shaolu Li†, Yingqin Hou†, Yali Hu, Jin Yu, Wei Wei* and Hua Lu*, “Phosphatase-triggered cell-selective release of a Pt(IV)-backboned prodrug-like polymer for an improved therapeutic index”, Biomater. Sci. 2017, 5, 1558 – 1566. (†equal contribution) [PDF]

[29] Wei Xiong, Xiaohui Fu, Yaoming Wan, Yunlong Sun, Zhibo Li* and Hua Lu*, “Synthesis and multimodal responsiveness of poly(α-amino acid)s bearing OEGylated azobenzene side-chains”, Polym. Chem., 2016, 7, 6375-6382 [PDF]

[28] Yingqin Hou, † Jingsong Yuan, † Yu Zhou, Jin Yu, and Hua Lu*, “A Concise Approach to Site-Specific Topological Protein-Poly(amino acid) Conjugates Enabled by in Situ -Generated Functionalities”, J. Am. Chem. Soc. 2016, 138, 10995-11000. (†equal contribution) [PDF] 

[Highlighted by Acta Polymerica Sinica][Highlighted by X-MOL]

[27] Guangqi Wu, Hua Lu*, “Progress in Biomedical Applications of Functionalized Nucleic Acid Nanodevices (NANDs)”, ChemNanoMat 2016, 2, 354-363. [PDF]

[26] Jingsong Yuan, Yunlong Sun, Jingyu Wang, and Hua Lu*, “Phenyl Trimethylsilyl Sulfide-Mediated Controlled Ring-Opening Polymerization of α‐Amino Acid N‐Carboxyanhydrides”, Biomacromolecules, 2016, 17, 891-896. [PDF]

[25] Yunlong Sun, Yingqin Hou, Xuhao Zhou, Jingsong Yuan, Jingyu Wang, and Hua Lu*,”Controlled Synthesis and Enzyme-Induced Hydrogelation of Poly(L‑phosphotyrosine)s via Ring-Opening Polymerization of α‑Amino Acid N‑Carboxyanhydride” ACS Macro Letters  2015, 4,1000-1003. [PDF]

[24] Hua Lu†, Quan Zhou†, Vishal Deshmukh†, Hardeep Phull, Jennifer Ma, Virginie Tardif, Rahul R. Naik, Claire Bouvard, Yong Zhang, Seihyun Choi, Brian R. Lawson, Shoutian Zhu, Chan Hyuk Kim*, and Peter G. Schultz*, “Targeting Human C-Type Lectin-Like Molecule-1 (CLL1) with a Bispecific Antibody for Acute Myeloid Leukemia Immunotherapy”, Angew. Chem. Int. Ed. 2014, 53, 9841-9845. [PDF]

[23] Nan Zheng, Lichen Yin, Ziyuan Song, Liang Ma, Haoyu Tang, Nathan P. Gabrielson, Hua Lu,  and Jianjun Cheng*, “Maximizing gene delivery efficiencies of cationic helical polypeptides via balanced membrane penetration and cellular targeting”, Biomaterials, 2014, 35, 1302-1314. [PDF]

[22] Hua Lu*, Jing Wang, Ziyuan Song, Lichen Yin, Yanfeng Zhang, Haoyu Tang, Chunlai Tu, Yao Lin*and Jianjun Cheng*, ” Recent Advances in Amino Acid N-Carboxyanhydrides and Synthetic Polypeptides: Chemistry, Self-assembly and Biological Applications”, Chem. Comm. 2014, 50, 139-155. [PDF]

[21] Hua Lu, Danling Wang, Stephanie Kazane, Tsotne Javahishvili, Feng Tian, Frank Song, Aaron Sellers, Barney Barnett and Peter G. Schultz*, “Site-specific Antibody-polymer Conjugates for siRNA Delivery “, J. Am. Chem. Soc., 2013, 135, 13885–13891. [PDF]

[20] Yanfeng Zhang, Qian Yin, Hua Lu, and Honwgwei Xia, Yao Lin Jianjun Cheng*, “PEG-Polypeptide Dual Brush Block Copolymers: Synthesis and Application in anoparticle Surface PEGylation”,  ACS Macro. Lett. 2013, 2, 809-813 [PDF]

[19] Lichen Yin, Haoyu Tang, Kyung Kim, Nan Zheng, Ziyuan Song, Nathan Gabrielson, Hua Lu, and Jianjun Cheng*, “Light-Responsive Helical Polypeptides Capable of Reducing Toxicity and Unpacking DNA toward Non-Viral Gene Delivery” Angew. Chemie. Int. Ed. 2013, 52, 9182-9186. [PDF]

[18] Jing Wang, Hongwei Xia, Yanfeng Zhang, Hua Lu, Ranjan Kamat, Andrey V. Dobrynin, Jianjun Cheng* and Yao Lin*, “Nucleation-Controlled Polymerization of Nanoparticles into Supramolecular Structures”, J. Am. Chem. Soc., 2013, 135, 11417-11420. Featured as the cover art of Volume 135, Issue 31, August 7, 2013 [PDF]

[17] Jonathan Yen, Yanfeng Zhang, Nathan Gabrielson, Lichen Yin, Linna Guan, Isthier Chaudhury, Hua Lu, Fei Wang* and Jianjun Cheng*, “Cationic, helical polypeptide-based gene delivery for IMR-90 fibroblasts and human embryonic stem cell”, Biomater. Sci. 2013, 1, 719-727 [PDF]

[16] Lichen Yin, Ziyuan Song, Kyung Hoon Kim, Nan Zheng, Haoyu Tang, Hua Lu, Nathan Gabrielson, Jianjun Cheng*, “Reconfiguring the architectures of cationic helical polypeptides to control non-viral gene delivery”, Biomaterials 2013, 34, 2340-2349. [PDF]

[15] Haoyu Tang, Lichen Yin, Hua Lu, and Jianjun Cheng*, “Water-Soluble Poly(L-serine)s with Elongated and Charged Side-Chains: Synthesis, Conformations and Cell-Penetrating Properties”, Biomacromolecules 2012, 13, 2609-2615. [PDF]

[14] Nathan Gabrielson, Hua Lu, Lichen Yin, Kyung Hoon Kim and Jianjun Cheng*, “A Cell-Penetrating Helical Polymer for siRNA Delivery to Mammalian Cells “, Mol. Ther. 2012, 20, 1599-1609. [PDF]

[13] Nathan Gabrielson†, Hua Lu†, Lichen Yin, Dong Li, Fei Wang, and Jianjun Cheng*,”A Reactive Cationic α-Helical Polypeptide Template for Non-Viral Gene Delivery”, Angew. Chem. Int. Ed. 2012, 51, 1143-1147 (†equal contribution) highlighted by Chemical and Engineering News, issue of Dec. 19, 2011; reported by ScienceDaily, PhysOrg, and EurekAlert! etc. [PDF]

[12] Kuan-Ju Chen, Li Tang, Mitch Andre Garcia, Hao Wang, Hua Lu, Wei-Yu Lin, Shuang Hou, Qian Yin, Clifton K.-F. Shen, Jianjun Cheng* and Hsian-Rong Tseng*, “The therapeutic efficacy of camptothecin-encapsulated supramolecular nanoparticles”, Biomaterials 2012, 33, 1162-1169. [PDF]

[11] Hua Lu, Jing Wang, Yugang Bai, Jason Long, Shiyong Liu, Yao Lin* and Jianjun Cheng*, “Ionic Polypeptides with Unusual Helical Stability”, Nature Commun. 2011, 2, 206. Reported by NSF, ScienceDaily, PhysOrg, EurekAlert! and ChemistryViews etc. [PDF]

[10] Jing Wang, Hua Lu, Ranjan Kamat , Sai Venkatesh Pingali , Volker S. Urban, Jianjun Cheng* and Yao Lin*, “Supramolecular Polymerization from Polypeptide-Grafted Comb Polymers”, J. Am. Chem. Soc. 2011, 133, 12906-12909. Highlighted by Chemical and Engineering News, issue of Aug. 15, 2011. [PDF]

[9] Jing Wang, Hua Lu, Yuan Ren, Yanfeng Zhang, Martha Morton, Jianjun Cheng* and Yao Lin*, ” Interrupted Helical Structure of Grafted-Polypeptides in Brush-like Macromolecules”, Macromolecules 2011, 44, 8699-9709. [PDF]

[8] Hua Lu, Yugang Bai, Jing Wang, Yao Lin and Jianjun Cheng*, “Controlled Ring-Opening Polymerization of γ-(4-Vinylbenzyl)-L-Glutamate N-Carboxyanhydride for the Synthesis of Functional Polypeptides”, Macromolecules 2011, 44, 6237-6240; Featured as the cover art of Macromolecules, Volume 44, Issue16, August 23, 2011 [PDF]

[7] Yanfeng Zhang, Hua Lu, Yao Lin and Jianjun Cheng*, “Water-Soluble Polypeptides with Elongated, Charged Side Chains Adopt Ultrastable Helical Conformations”, Macromolecules 2011, 44, 6641-6644. [PDF]

[6] Yugang Bai, Hua Lu, Ettigounder Ponnusamy, and Jianjun Cheng*, “Synthesis of Hybrid Block Copolymers via Integrated Ring-Opening Metathesis Polymerization and Polymerization of NCA “, Chem. Comm. 2011, 47, 10830-10832. [PDF]

[5] Hua Lu, Jing Wang, Yao Lin* and Jianjun Cheng*, “One-Pot Synthesis of Brush-Like Polymers via Integrated Ring-Opening Metathesis Polymerization and Polymerization of Amino Acid N-Carboxyanhydrides”, J. Am. Chem. Soc. 2009, 131, 13582-13583. Highlighted by Chemical and Engineering News, issue of Sept. 14, 2009. [PDF]

[4] Hua Lu and Jianjun Cheng*, “N-Trimethylsilyl amines for controlled ring-opening polymerization of amino acid N-carboxyanhydrides and facile end group functionalization of polypeptides”, J. Am. Chem. Soc. 2008, 130, 12562-12563. [PDF]

[3] Hua Lu and Jianjun Cheng*, “Hexamethyldisilazane-Mediated Controlled Polymerization of alpha-Amino Acid N-Carboxyanhydrides”, J. Am. Chem. Soc. 2007, 129, 14115-14116. [PDF]

[2] Xiaoyu Cao, Hong Zi, Wei Zhang, Hua Lu, and Jian Pei*, “Star-shaped and Linear Nanosized Molecules Functionalized with Hexa-peri-hexabenzocoronene: Synthesis and Optical Properties” J. Org. Chem. 2005, 70, 3645-3653. [PDF]

[1] Xiaoyu Cao, Wenbin Zhang, Jinliang Wang, Xinhua Zhou, Hua Lu, and Jian Pei*, “Extended π–Conjugated Dendrimers Based on Truxene” J. Am. Chem. Soc. 2003, 125, 12430-12431. [PDF]