Research News, Jan 6, 2010

 

研究室工作进展 January 6, 2010
 
Isolation and X-ray Structure of a Trimeric 1,4-Dilithio-1, 3-butadiene and a Dimeric Me3Si-substituted 1,4-dilithio-1,3-butadiene
 
Lantao Liu, Wen-Xiong Zhang,* Qian Luo, Heng Li, and Zhenfeng Xi*
 
Organometallics 2010, 29, 278-281.
 
 
 
The X-ray crystallographic structures of a trimeric all-alkyl substituted 1,4-dilithio-1,3- butadiene with a Li6 pseudooctahedron as well as of the dimeric Me3Si-substituted 1,4-dilithio-1,3-butadiene with a Li4 tetrahedron are reported.
 
本工作背景介绍
本研究小组自1999年发现1,4-双锂-1,3-丁二烯衍生物具有不同与常见单锂金属有机合成试剂的反应模式以来,一直努力建立合成该类衍生物纯品的有效方法,以便最终将这类衍生物发展成方便使用的双锂金属有机合成试剂;同时,我们希望了解该类双锂金属有机化合物尤其是全烷基取代的衍生物的结构与成键模式。经过几代研究生的努力,最终在2009年由刘澜涛同学在张文雄老师的指导下完成该工作,可以方便地以80%以上的分离收率获得克级以上多种衍生物的晶体(其中之一如图),并作为试剂方便地用于进一步的反应。
 
 
Background of this work
1,4-Dilithio-1,3-butadienes found by our group in 1999 demonstrate different reaction patterns from commonly widely used mono-Li reagents. Since then, we have tried to establish an efficient synthetic method to get pure compounds, aiming at developing such compounds as useful organo-di-lithio reagents. After many trials by several graduate students, this goal was finally achieved in 2009 by Mr. Lantao Liu and Dr. Wen-Xiong Zhang. Most of such derivatives now can be obtained in this group as fine crystalline compounds in over 80% isolated yields with gram-scale. The picture shows one of such derivatives, which are kept in cooler and used when needed.