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Publications

100. Controlling SpyTag/SpyCatcher Reactivity via Redox-Gated Conformational Restriction. ACS Macro Lett. 2018, 7 , 1388-1393
Posted on:2020-09-19

Wu, W.-H.; Wei, J.; Zhang, W.-B.* Controlling SpyTag/SpyCatcher Reactivity via Redox-Gated Conformational Restriction. ACS Macro Lett. 2018, 7 , 1388-1393.

 

 

Abstract:  Herein, we report that the reactivity of genetically encoded SpyTag/SpyCatcher chemistry can be manipulated via redox-gated conformational restriction, which facilitates the preparation of all-protein-based hydrogel with latent reactive sites for subsequent covalent functionalization.